지방줄기세포

지방줄기세포란?

    • 본인 피하지방에서 간단하게 채취할 수 있음
    • 다량의 줄기세포 채취 가능 분화능력이 뛰어남
    • 보관연령 제한 없으며 세포의 안전성과 활성이 검증 됨

보관의 필요성

bullet 왜 지방줄기세포를 보관해야 할까요?

노화나 질환 등으로 몸 안에 남아 있는 줄기세포의 수와 활성이 감소되면 체내의 ‘항상성 유지’가 힘들게 됩니다

    • 정상적인 건강한 생리적 기능을 유지하기 위해서는 젊고 활성화 된 줄기세포가 필요합니다.
    • 지방줄기세포를 보관하시면 노화되고 부족한 내 몸의 줄기세포를 젊은 세포로 보충해 줄 수 있습니다.
    • 지방줄기세포를 보관 하시면 향후 무릎 연골 생성에 큰 도움을 받을 수 있습니다.
    • 지방줄기세포를 보관하시면 골수기능 강화를 통해 신체 기능을 유지하고 회복하는 데 큰 도움을 받을 수 있습니다.

* 몸도 기억도 늙지 않는 소망, 줄기세포의 미래입니다

지방줄기세포 보관방법

지방유래 중간엽줄기세포 관련 바이오스타의 주요 논문

Human adipose tissue-derived mesenchymal stem cells inhibit T-cell lymphoma growth in vitro and in vivo.

Ahn JO, Chae JS, Coh YR, Jung WS, Lee HW, Shin IS, Kang SK, Youn HY.
Anticancer Res. 2014 Sep;34(9):4839-47.PMID: 25202065

Intra-articular injection of mesenchymal stem cells for the treatment of osteoarthritis of the knee: A proof-of-concept clinical trial.

Jo CH, Lee YG, Shin WH, Kim H, Chai JW, Jeong EC, Kim JE, Shim H, Shin JS, Shin IS, Ra JC, Oh S, Yoon KS.
Stem Cells. 2014 Jan 21. doi: 10.1002/stem.1634. [Epub ahead of print]PMID: 24449146

The therapeutic effects of human adipose-derived stem cells in Alzheimer’s disease mouse models.

Chang KA, Kim HJ, Joo Y, Ha S, Suh YH.
Neurodegener Dis. 2014;13(2-3):99-102. doi: 10.1159/000355261. Epub 2013 Oct 23.PMID: 24157626

Transplantation of human adipose tissue-derived stem cells delays clinical onset and prolongs life span in ALS mouse model.

Kim KS, Lee HJ, An J, Kim YB, Ra JC, Lim I, Kim SU.Cell Transplant. 2013 Sep 18. PMID: 24070071

Human adipose tissue-derived mesenchymal stem cells improve cognitive function and physical activity in ageing mice.

Park D, Yang G, Bae DK, Lee SH, Yang YH, Kyung J, Kim D, Choi EK, Choi KC, Kim SU, Kang SK, Ra JC, Kim YB.
J Neurosci Res. 2013 May;91(5):660-70. doi: 10.1002/jnr.23182. Epub 2013 Feb 13.PMID: 23404260

In vivo differentiation of undifferentiated human adipose tissue-derived mesenchymal stem cells in critical-sized calvarial bone defects.

Choi JW, Park EJ, Shin HS, Shin IS, Ra JC, Koh KS.
Ann Plast Surg. 2014 Feb;72(2):225-33. doi: 10.1097/SAP.0b013e31825f70f5.PMID: 23221992

The preventive and therapeutic effects of intravenous human adipose-derived stem cells in Alzheimer’s disease mice.

Kim S, Chang KA, Kim Ja, Park HG, Ra JC, Kim HS, Suh YH.
PLoS One. 2012;7(9):e45757. doi: 10.1371/journal.pone.0045757. Epub 2012 Sep 26.PMID: 23049854

Effect of an adipose-derived stem cell and nerve growth factor-incorporated hydrogel on recovery of erectile function
in a rat model of cavernous nerve injury.

Kim IG, Piao S, Lee JY, Hong SH, Hwang TK, Kim SW, Kim CS, Ra JC, Noh I, Lee JY.Tissue Eng Part A. 2013 Jan;19(1-2):14-23. doi: 10.1089/ten.TEA.2011.0654. Epub 2012 Sep 4.PMID: 22834730

Journey of mesenchymal stem cells for homing: strategies to enhance efficacy and safety of stem cell therapy.

Kang SK, Shin IS, Ko MS, Jo JY, Ra JC.
Stem Cells Int. 2012;2012:342968. doi: 10.1155/2012/342968. Epub 2012 Jun 13.PMID: 22754575

Safety and effect of adipose tissue-derived stem cell implantation in patients with critical limb ischemia: a pilot study.

Lee HC, An SG, Lee HW, Park JS, Cha KS, Hong TJ, Park JH, Lee SY, Kim SP, Kim YD, Chung SW, Bae YC, Shin YB, Kim JI,
Jung JS. Circ J. 2012;76(7):1750-60. Epub 2012 Apr 12.PMID: 22498564

In vitro migration capacity of human adipose tissue-derived mesenchymal stem cells reflects their expression of  receptors for chemokines and growth factors.

Baek SJ, Kang SK, Ra JC.Exp Mol Med. 2011 Oct 31;43(10):596-603. doi: 10.3858/emm.2011.43.10.069.PMID: 21847008

Establishment of efficacy and safety assessment of human adipose tissue-derived mesenchymal stem cells (hATMSCs) in a nude rat femoralsegmental defect model.

Choi HJ, Kim JM, Kwon E, Che JH, Lee JI, Cho SR, Kang SK, Ra JC, Kang BC.
J Korean Med Sci. 2011 Apr;26(4):482-91. doi: 10.3346/jkms.2011.26.4.482. Epub 2011 Mar 28.PMID: 21468254